Toby Wise Computational psychiatry | Anxiety and depression Investigating neural & computational mechanisms underlying symptoms of anxiety and depression


Wise, T. & Dolan, R.J. (2019). Associations between aversive learning processes and transdiagnostic psychiatric symptoms revealed by large-scale phenotyping. bioRxiv.

Wise, T., Zbozinek, T.D., Michelini, G., Hagan, C.C., Mobbs, D. (2020). Changes in risk perception and protective behavior during the first week of the COVID-19 pandemic in the United States. PsyArXiv.

Valton, V., Wise, T. , Robinson, O.J. (2020). The Importance of Group Specification in Computational Modelling of Behaviour. PsyArXiv


Wise, T.*, Patrick, F.*, Meyer M., Mazibuko, M., Oates A.E., van der Bijl, A.H.M, Danjou, P., O’Connor S.M., Doolin E., Wooldridge C., Rathjan, D., Macare, M., Williams, S.C.R., Perkins, A.M. & Young, A.H. (2020). Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalised Anxiety Disorder. Biological Psychiatry


Wise, T., Michely, J., Dayan, P., Dolan, R.J. (2019). A computational account of threat-related attentional bias. PLOS Computational Biology, 15 (10)


Marwood, L., Wise, T., Perkins, A. M., & Cleare, A. J. (2018). Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety. Neuroscience & Biobehavioral Reviews.

Wise, T., Marwood, L., Perkins, A. M., Herane‐Vives, A., Williams, S. C. R., Young, A. H., … & Arnone, D. (2018). A morphometric signature of depressive symptoms in unmedicated patients with mood disorders. Acta Psychiatrica Scandinavica, 138(1), 73-82.

Wise, T., Taylor, M. J., Herane-Vives, A., Gammazza, A. M., Cappello, F., Lythgoe, D. J., … & Arnone, D. (2018). Glutamatergic hypofunction in medication-free major depression: Secondary effects of affective diagnosis and relationship to peripheral glutaminase. Journal of affective disorders, 234, 214-219.

Arnone, D, Wise, T., Walker, C., Cowen, P. J., Howes, O., & Selvaraj, S. (2018). The effects of serotonin modulation on medial prefrontal connectivity strength and stability: A pharmacological fMRI study with citalopram. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 84, 152-159.

Herane‐Vives, A., de Angel, V., Papadopoulos, A., Wise, T., Chua, K. C., Strawbridge, R., … & Cleare, A. J. (2018). Short‐term and long‐term measures of cortisol in saliva and hair in atypical and non‐atypical depression. Acta Psychiatrica Scandinavica, 137(3), 216-230.

Herane-Vives, A., Fischer, S., de Angel, V., Wise, T., Cheung, E., Chua, K. C., … & Cleare, A. J. (2018). Elevated fingernail cortisol levels in major depressive episodes. Psychoneuroendocrinology, 88, 17-23.


Herane-Vives, A. H., Wise, T., De Angel, V., Arnone, D., Tsapekos, D., Papadopoulos, A., … & Cleare, A. (2017). Cortisol levels in typical and non-typical major depressive episodes, using hair and saliva specimens. Psychoneuroendocrinology, 83, 44-45.

Wise, T.. Marwood, L, Perkins, A.M., Herane, A., Joules, R., Lythgoe, D., Luh, W., Williams, S.C.R., Young, A.H., Cleare, A.J., Arnone, D. (2017) Instability of Default Mode Dynamic Functional Connectivity in Major Depression: A Two-Sample Confirmation Study. Translational Psychiatry. 7(4), e1105

Wise, T., Radua, J., Via, E., Cardoner, N., Abe, O., Adams, T. M., … & Arnone, D. (2017). Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis. Molecular psychiatry, 22(10), 1455.


Wise, T., Arnone, D., Marwood, L., Zahn, R., Lythe, K.E., Young, A.H. (2016). Recruiting for research studies using online public advertisements: examples from research in affective disorders. Neuropsychiatric disease and treatment. 12, 279-285.

Wise, .T, Radua, J., Nortje, G., Cleare, A.J., Young, A.H., & Arnone, D. (2016) Voxel-Based Meta-Analytical Evidence of Structural Disconnectivity in Major Depression and Bipolar Disorder. Biological psychiatry. 79, 293-302. (featured on the cover of the February 2016 issue)


Herane-Vives, A.H., De Angel, V., Papadopoulos, A., Strawbridge, R., Wise, T., Young, A.H., Arnone, D. and Cleare, A.J. (2015). The relationship between cortisol, stress and psychiatric illness: New insights using hair analysis. Journal of psychiatric research. 70, 38-49.


Wise, T., Cleare, A.J., Herane, A., Young, A.H., & Arnone, D. (2014). Diagnostic and therapeutic utility of neuroimaging in depression: an overview. Neuropsychiatric disease and treatment. 10, 1509-1522.